Disease: Primary Sjögren's syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TSLP Q969D9 thymic stromal lymphopoietin 4.0E-03 0.486 0.808
TRIM21 P19474 tripartite motif containing 21 3.4E-09 0.485 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
SST P61278 somatostatin Signaling 0.34 0.399 0.885
SLC22A1 O15245 solute carrier family 22 member 1 Transporter 1.5E-22 0.556 0.731
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PSMB9 P28065 proteasome 20S subunit beta 9 2.7E-03 0.514 0.808
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PDCD1 Q15116 programmed cell death 1 0.42 0.402 0.846
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MIR146A microRNA 146a 0.398 0.885
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
IL22 Q9GZX6 interleukin 22 1.9E-04 0.393 0.885